The virulence-enhancing factor of mucins. 1. A biological assay of virulence-enhancing activity

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The Virulence-enhancing Factor of Mucins

In preceding papers of this series (Smith, 1950a, b, 1951a; Smith, Harris-Smith & Stanley, 1951) the virulence-enhancing action of mucin has been shown to be a synergic combination of a viscous medium, a particulate residue Iand a more specific 'third factor'. The activity of the latter, in a biological assay in which the other two factors were kept constant (Smith et al. 1951), was shown to re...

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The Virulence-Enhancing Factor of Mucins 4. THE ROLE OF PARTICULATE INSOLUBLE MATTER AND A VISCOUS MEDIUM IN VIRULENCE ENHANCEMENT, WITH A REVISED ASSAY OF THE THIRD FACTOR INVOLVED BY H. SMITH,

In Part 3 (Smith, 1951) of this series a virulenceenhancing fraction of hog gastric mucin was separated from the insoluble particulate residue. This residue had an adjuvant action on the enhancement ofthe virulence by the activefactor comparable with that already demonstrated (Smith, 1950b) for the viscosity of the original mucin. However, using a biological assay involving a medium of constant...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1950

ISSN: 0306-3283

DOI: 10.1042/bj0460352